Bioreactors in Bioprocessing

• Describe the purpose of a bioreactor in bioprocessing
• Describe the structure of a typical stainless steel bioreactor
• Distinguish between the different operating modes of a bioreactor
• Explain how effective mixing can be achieved in a bioreactor
• List the process parameters that are typically monitored and controlled when operating a bioreactor
• Describe the various risk factors that can compromise bioreactor sterility and how contamination of a bioreactor can be prevented
• Explain the concept of ‘mass transfer’ in bioprocessing
• Explain the relationship between metabolism, heat generation, and agitation in bioprocessing

Learner Benefits:

• Develop a foundational understanding of the purpose and functions of bioreactors in bioprocessing, including their design, operation, and the types of products they produce.

• Learn about the different types of bioreactors, their components, and the operating modes used to achieve optimal bioprocessing conditions, including batch, continuous, and fed-batch operations.

• Understand the process parameters that are critical for bioreactor operation, such as temperature, pH, dissolved oxygen, and mixing and how these parameters are monitored and controlled to ensure product quality and consistency.

• Identify the risk factors that can compromise bioreactor sterility and learn strategies for preventing contamination, including Clean in Place (CIP) and Steam in Place (SIP) procedures.

• Explore the concepts of mixing and mass transfer within bioreactors and their impact on product yield and quality.

    Animations
   Voice Over
    Knowledge Checks
    Assessments
   SCORM/AICC compatible
    Full Screen