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Founded in 1998 in Dublin, Ireland, Skillpad's team of industry-experienced Subject Matter Experts and Consultants believes Pharma, Biopharma, and Life Science Industry manufacturing companies can achieve production excellence with improved performance, productivity & compliance, as well as reduced losses & down-time, if they have KNOWLEDGE CONSISTENCY in all critical areas of manufacturing operations.

With 25 years in business, and offices in Europe, the USA and Canada, Skillpad has helped customers all over the world with Life Science Industry Knowledge challenges. We are fully dedicated to the idea that Knowledge Consistency is more achievable than ever using the latest technology and advanced knowledge transfer and management tools.

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    Understanding Dissolution

    Explore the fundamentals of dissolution testing and its critical role in the pharmaceutical industry. This module provides a detailed look at how a solid dosage drug form dissolves and is absorbed into the bloodstream, focusing on factors like polarity, temperature, pH, and agitation. Understand the principles of ‘in vivo’ and ‘in vitro’ dissolution analyses and learn about single-point and multi-point testing methods. Through animations and interactive explorations, grasp how dissolution testing ensures drug efficacy and compliance with regulatory standards.

    Whether for onboarding or annual refresher training, this Module is seamlessly deployable on any LMS and can be tailored to your company’s exact needs.

      Duration: 30 Mins
    Grade: Core Library

    SKU: PPL-1210-SPL01-EN Category: Tag:

    Description

    Learning Objectives:

    • Define the term ‘dissolution’
    • Explain the purpose of dissolution testing
    • List and describe the factors that affect dissolution
    • Describe what happens to a solid dosage drug form in the human body after it is swallowed
    • Explain the difference between ‘in vivo’ and ‘in vitro’ dissolution analysis
    • Explain why in vitro dissolution analysis is important
    • Explain the difference between single-point and multi-point dissolution tests

    Learner Benefits:

    • Clear Comprehension of Dissolution Fundamentals: Master the definition and essential purpose of dissolution, including the physical and chemical processes that influence how drugs dissolve.
    • Insight into Critical Testing Parameters: Recognize the factors impacting dissolution, such as solvent polarity, temperature, pH, and stirring, enhancing your understanding of formulation behavior in various environments.
    • Practical Understanding of Drug Absorption: Learn how a solid dosage form disintegrates and dissolves in the gastrointestinal tract before crossing into the bloodstream, crucial for assessing bioavailability.
    • Differentiation Between Analytical Techniques: Distinguish between ‘in vivo’ and ‘in vitro’ testing, appreciating the importance of simulating human conditions in laboratory settings to predict drug performance.
    Module Features:

        Animations
       Voice Over
        Knowledge Checks
        Assessments
       SCORM/AICC compatible
        Full Screen

    Keywords

    • Bioavailability
    • Dissolution Testing
    • Drug Absorption
    • Drug Disintegration
    • Gastrointestinal Tract
    • In Vitro Analysis
    • In Vivo Analysis
    • Polarity
    • Solid Dosage Form
    • Solvent
    • Stirring/Agitation
    • Temperature
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